abstract：INTRODUCTION:In vivo, the airway epithelium stretches and relaxes with each respiratory cycle, but little is known about the effect this pattern of elongation and relaxation has on bronchial epithelial cells. We have used a model of cell deformation to measure the effect of stretch on inflammatory cytokine release by t...

journal_title：Respiratory medicine

authors： Thomas RA,Norman JC,Huynh TT,Williams B,Bolton SJ,Wardlaw AJ

更新日期：2006-09-01 00:00:00

abstract：:Intrapulmonary percussive ventilation (IPV) is a ventilatory technique that delivers bursts of high-flow respiratory gas into the lung at high rates, intended for treating acute respiratory failure and for mobilization of secretions. We performed a study, aimed at assessing the physiological response to IPV, on patien...

journal_title：Respiratory medicine

authors： Nava S,Barbarito N,Piaggi G,De Mattia E,Cirio S

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Mortality rates from lung cancer are known to vary considerably between countries. Differences in patients, disease, investigation and treatment are thought to account for some survival shortfalls but it is not known whether differences in collection or processing of data also contribute. METHODOLOGY:We sea...

journal_title：Respiratory medicine

authors： Butler CA,Darragh KM,Currie GP,Anderson WJ

更新日期：2006-09-01 00:00:00

abstract：:Although the principles of asthma management are well established in Europe, the available data indicate that asthma in patients is not well controlled. Many patients derive incomplete benefit from their inhaled medication because they do not use inhaler devices correctly and this may compromise asthma control. The Ae...

journal_title：Respiratory medicine

authors： Crompton GK,Barnes PJ,Broeders M,Corrigan C,Corbetta L,Dekhuijzen R,Dubus JC,Magnan A,Massone F,Sanchis J,Viejo JL,Voshaar T,Aerosol Drug Management Improvement Team.

更新日期：2006-09-01 00:00:00

abstract：RATIONALE:Exercise-induced bronchoconstriction (EIB) increases in cold and dry air and decreases in humid air in subjects with asthma. Few reports have reported on the effect of humid environment upon exercise capacity in subjects with EIB. OBJECTIVE:The primary aim of the present study was to examine the effect of ch...

journal_title：Respiratory medicine

authors： Stensrud T,Berntsen S,Carlsen KH

更新日期：2006-09-01 00:00:00

abstract：INTRODUCTION:Non-invasive positive pressure ventilation (NIPPV) is an effective treatment in respiratory failure. Continuous positive pressure (CPAP) may also be useful in acute hypoxaemic patients. Supplementary oxygen is usually necessary in both systems. However, the inspired oxygen fraction (FiO2) delivered by a NI...

journal_title：Respiratory medicine

authors： Samolski D,Antón A,Güell R,Sanz F,Giner J,Casan P

更新日期：2006-09-01 00:00:00

abstract：AIM:To compare the estimated size of spontaneous pneumothoraces using the established Rhea inter-pleural distances method with the CT-derived Collins method. METHOD:Adult patients with spontaneous pneumothorax treated conservatively were identified from the ED databases. X-rays were reviewed independently by two resea...

journal_title：Respiratory medicine

authors： Kelly AM,Weldon D,Tsang AY,Graham CA

更新日期：2006-08-01 00:00:00

abstract：:We report the first study of triple-dose immunotherapy with heat-killed Mycobacterium vaccae (SRL 172) combined with short-course, directly observed chemotherapy in newly diagnosed pulmonary tuberculosis patients. The study was carried out in Rosario, Argentina, where single-dose immunotherapy with M. vaccae has previ...

journal_title：Respiratory medicine

authors： Dlugovitzky D,Fiorenza G,Farroni M,Bogue C,Stanford C,Stanford J

更新日期：2006-06-01 00:00:00

abstract：STUDY OBJECTIVES:To test if morbid obesity causes pulmonary function changes and if massive weight loss have effect on pulmonary function (especially in subjects with BMI>or=60 kg/m(2)). PARTICIPANTS:Thirty-nine morbid obese subjects before and after massive weight loss. MEASUREMENTS AND RESULTS:Patients had baseline...

journal_title：Respiratory medicine

authors： Santana AN,Souza R,Martins AP,Macedo F,Rascovski A,Salge JM

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:Mesothelioma invades the tracts made by chest instrumentation. Prophylactic radiotherapy is effective at preventing malignant seeding at these sites. METHODS:We assessed the use and effectiveness of radiotherapy at our centre in 39 of the 40 patients identified with mesothelioma between January 2000 and Sep...

journal_title：Respiratory medicine

authors： West SD,Foord T,Davies RJ

更新日期：2006-06-01 00:00:00

abstract：:The N(2) slope is an index of inhomogeneous distribution of ventilation and has been suggested to be suited for early testing of chronic obstructive pulmonary disease (COPD) in smokers. The aim of the present study was to examine the association between the fraction of exhaled nitric oxide (FENO) and the N(2) slope in...

journal_title：Respiratory medicine

authors： Olin AC,Andelid K,Vikgren J,Rosengren A,Larsson S,Bake B,Ekberg-Jansson A

更新日期：2006-06-01 00:00:00

abstract：:A 56-year-old female patient, developing ALK-negative anaplastic T cell lymphoma 7 years after the diagnosis of sarcoidosis with clinical and histopathological features of tuberculosis has been presented. We herein present concurrent occurrence of the sarcoidosis, lymphoma and tuberculosis along with the confusing fin...

journal_title：Respiratory medicine

authors： Tufan A,Ranci O,Sungur A,Topeli A,Haznedaroglu I,Cöplü L

更新日期：2006-05-01 00:00:00

abstract：OBJECTIVE:Dipyrone (Novalgin) is an effective analgesic, antipyretic agent also with spasmolytic effects on various types of smooth muscles. It has recently been reported that dipyrone relaxes tracheal smooth muscle of guinea pig. In this present study, we aimed to investigate whether this and previously reported in vi...

journal_title：Respiratory medicine

authors： Gulmez SE,Tulunay FC,Beder S,Kayacan O,Karnak D

更新日期：2006-05-01 00:00:00

abstract：:Vascular endothelial growth factor (VEGF) may be one of the pathophysiologic links in the association between obstructive sleep apnea-hypopnea and cardiovascular disease. Morning serum VEGF levels are increased in children with obstructive sleep apnea. However, release of VEGF by platelets and leukocytes during blood ...

journal_title：Respiratory medicine

authors： Kaditis AG,Alexopoulos EI,Karadonta I,Kostadima E,Kiropoulos T,Gourgoulianis K,Syrogiannopoulos GA

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:Idiopathic pulmonary fibrosis (IPF) is a fibroproliferative disorder. Cytokines contribute an important but yet undefined role to its pathogenesis. OBJECTIVES:The present study aims to compare serum levels of cytokines involved in Th-1 and Th-2 immunity, such as interleukins (IL) IL-2, IL-4, IL-8, IL-10, in...

journal_title：Respiratory medicine

authors： Tsoutsou PG,Gourgoulianis KI,Petinaki E,Germenis A,Tsoutsou AG,Mpaka M,Efremidou S,Molyvdas PA

更新日期：2006-05-01 00:00:00

abstract：STUDY OBJECTIVE:Two modes of noninvasive home mechanical ventilation (NIHMV) with volumetric ventilators were compared in patients with chronic respiratory failure. DESIGN:Retrospective, parallel-group, comparative study. SETTING:Third-level teaching Hospital in Barcelona (Spain). PATIENTS AND METHODS:We studied 110...

journal_title：Respiratory medicine

authors： Muñoz X,Crespo A,Marti S,Torres F,Ferrer J,Morell F

更新日期：2006-04-01 00:00:00

abstract：:Gemcitabine is a newer pyrimidine analog used for the treatment of solid tumors. Though generally considered safe, it can cause pulmonary toxicity, which is generally mild and reversible. The purpose of this publication is to document a case of adult respiratory distress syndrome (ARDS) caused by Gemcitabine administr...

journal_title：Respiratory medicine

authors： Davidoff S,Shah RD,Arunabh T

更新日期：2006-04-01 00:00:00

abstract：:In this economic evaluation, conducted alongside a randomized, double-blind clinical trial, economic data were collected from 339 patients with moderate-persistent asthma randomized to receive twice-daily, double-blind treatment with budesonide/formoterol 160/4.5 microg in a single inhaler (n=166) or fluticasone propi...

journal_title：Respiratory medicine

authors： Ericsson K,Bantje TA,Huber RM,Borg S,Bateman ED

更新日期：2006-04-01 00:00:00

abstract：:Gastroesophageal reflux disease (GERD) is commonly associated with asthma; however, frequency in nonatopic children with asthmatic symptoms is unknown. The aim of this study was to determine the frequency of gastroesophageal reflux (GER) in nonatopic children with asthma-like airway disease that recur despite conventi...

journal_title：Respiratory medicine

authors： Yüksel H,Yilmaz O,Kirmaz C,Aydoğdu S,Kasirga E

更新日期：2006-03-01 00:00:00

abstract：STUDY OBJECTIVES:To determine the medications prescribed to patients with chronic obstructive pulmonary disease (COPD) and their relationship to health-related quality of life (HRQL). METHODS:Cross-sectional study of 611 consecutive patients with stable, mild-to-severe COPD who attended at the respiratory service of a...

journal_title：Respiratory medicine

authors： Esteban C,Moraza J,Quintana JM,Aburto M,Capelastegui A

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Asthma treatment per Global Initiative for Asthma (GINA) guidelines targets airway remodeling and achievement of normal lung function. OBJECTIVE:To study inhaled steroid therapy on airway remodeling and achievement of normal lung function. SUBJECTS AND SET UP: Asthmatic patients were followed over 5 years ....

journal_title：Respiratory medicine

authors： Bibi HS,Feigenbaum D,Hessen M,Shoseyov D

更新日期：2006-03-01 00:00:00

abstract：:Gastroesophageal reflux (GER) may induce respiratory symptoms (RS) through inhalation of acid gastric contents. To characterize the airway inflammation associated with this condition, 20 children [7.4 (0.9) yr old] with "difficult to treat" RS and a positive 24-h oesophageal pH monitoring (pHm) were studied and bronch...

journal_title：Respiratory medicine

authors： Sacco O,Silvestri M,Sabatini F,Sale R,Moscato G,Pignatti P,Mattioli G,Rossi GA

更新日期：2006-02-01 00:00:00

abstract：AIM:To assess the role of doctors who patients report as responsible of their disease, in moderate-severe chronic obstructive pulmonary disease (COPD), describing characteristics of patients and treatments use according to each type of doctor, and relating it to the way of access to hospital at the time of an exacerbat...

journal_title：Respiratory medicine

authors： Garcia-Aymerich J,Escarrabill J,Marrades RM,Monsó E,Barreiro E,Antó JM,EFRAM Investigators.

更新日期：2006-02-01 00:00:00

abstract：:The prevalence of tuberculosis in small solitary lesions of the lung obtained by video-assisted thoracoscopic surgery (VATS) is still unclear. Of 103 lung lesions resected by VATS in 98 patients (47 men, 51 women), 19 were identified macroscopically as inflammatory changes, 78 were neoplastic, and 6 were undefined. Pr...

journal_title：Respiratory medicine

authors： Hosaka N,Kameko M,Nishimura H,Hosaka S

更新日期：2006-02-01 00:00:00

abstract：:Nasal mucociliary clearance is a primary defense mechanism of the upper airways and may be acutely affected by nasal continuous positive airway pressure (nCPAP). nCPAP treatment is effective and safe. However, it can cause nasal side effects and contribute to a low compliance to the treatment. The aim of this study wa...

journal_title：Respiratory medicine

authors： de Oliveira LR,Albertini Yagi CS,Figueiredo AC,Saldiva PH,Lorenzi-Filho G

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Exhaled breath condensate (EBC) is simple to collect and as such a non-invasive method that has attracted substantial interest in the last few years. However, several methodological concerns have been raised and it has been difficult to reproduce results between different centres. Because of low concentratio...

journal_title：Respiratory medicine

authors： Tufvesson E,Bjermer L

更新日期：2006-01-01 00:00:00

abstract：:Systemic inflammation may be present in patients with chronic obstructive pulmonary disease (COPD). Exercise is known to elicit an inflammatory response. We hypothesized that the systemic inflammatory response to exercise might be exaggerated in COPD patients compared to healthy subjects. Sixteen COPD patients and 11 ...

journal_title：Respiratory medicine

authors： van Helvoort HA,van de Pol MH,Heijdra YF,Dekhuijzen PN

更新日期：2005-12-01 00:00:00

abstract：:Late allergic reactions (LAR) following allergen challenge occur in different compartments. We studied the kinetics of nasal and bronchial nitric oxide (NO) in mild asthmatics after allergen challenge. Twelve males with intermittent asthma (28 yr, FEV1 97% of predicted, PC20methacholine <8 mg/ml) and known LAR after b...

journal_title：Respiratory medicine

authors： Korn S,Beier J,Heilmann C,Kornmann O,Buhl R,Michael Beeh K

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Recurrent cough can be a clinical manifestation of rhinitis. However, it remains unclear if the association between rhinitis and recurrent cough among children is independent of asthma. OBJECTIVE:The aim of the present study was to determine, in a large longitudinal cohort, whether rhinitis is significantly...

journal_title：Respiratory medicine

authors： Sherrill DL,Guerra S,Minervini MC,Wright AL,Martinez FD

更新日期：2005-11-01 00:00:00

abstract：AIM:A high rate of seropositivity for antibodies against Helicobacter pylori has been found in many extra-gastrointestinal diseases. In addition, it has been reported that the risk of chronic bronchitis may be increased in subjects infected with H. pylori. This study was designed to determine the H. pylori seroprevalen...

journal_title：Respiratory medicine

authors： Kanbay M,Gur G,Akcay S,Yilmaz U

更新日期：2005-10-01 00:00:00

abstract：:The principals of rehabilitation medicine are to prevent muscle atrophy and improve mobility. Exacerbations of chronic obstructive pulmonary disease (COPD) are associated with muscle atrophy and yet many patients do not undergo pulmonary rehabilitation until they have been in stable health for some time. We investigat...

journal_title：Respiratory medicine

authors： Murphy N,Bell C,Costello RW

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:There has not been a comprehensive multi-center study investigating the microbial profile of community acquired pneumonia (CAP) in Taiwan. METHODS:A prospective study of adult CAP patients requiring hospitalization between December 2001 and April 2002 was carried out in 13 hospitals in Taiwan. Etiology was ...

journal_title：Respiratory medicine

authors： Lauderdale TL,Chang FY,Ben RJ,Yin HC,Ni YH,Tsai JW,Cheng SH,Wang JT,Liu YC,Cheng YW,Chen ST,Fung CP,Chuang YC,Cheng HP,Lu DC,Liu CJ,Huang IW,Hung CL,Hsiao CF,Ho M

更新日期：2005-09-01 00:00:00

abstract：OBJECTIVE:To assess whether tumor necrosis factor (TNF) antagonism can attenuate eosinophilic airway inflammation in patients with mild-to-moderate allergic asthma. DESIGN:Randomized, double-blind, placebo-controlled trial. SETTING:National Institutes of Health (NIH) Clinical Center. PATIENTS:Twenty-six patients wit...

journal_title：Respiratory medicine

authors： Rouhani FN,Meitin CA,Kaler M,Miskinis-Hilligoss D,Stylianou M,Levine SJ

更新日期：2005-09-01 00:00:00

abstract：:In high-school students, prevalence of smoking is high but few studies analyzed smoking in the student population according to nicotine content of smoked cigarettes and gender. We analyzed the responses to a questionnaire, including the modified Fagerström Tolerance Questionnaire (FTQ), administered to 555 students (3...

journal_title：Respiratory medicine

authors： Soresi S,Catalano F,Spatafora M,Bonsignore MR,Bellia V

更新日期：2005-08-01 00:00:00

abstract：:Abnormal heart rate recovery (HRR) after exercise, a marker of cardiac autonomic dysfunction, is associated with poor prognosis in various populations. As chronic obstructive pulmonary disease (COPD) is associated with cardiac autonomic dysfunction, we tested the hypothesis that patients with COPD have a lower HRR tha...

journal_title：Respiratory medicine

authors： Lacasse M,Maltais F,Poirier P,Lacasse Y,Marquis K,Jobin J,LeBlanc P

更新日期：2005-07-01 00:00:00

abstract：:Specific targeting of patients with a previous asthma hospitalisation could be more focused if predictors could be identified. This study was an observational retrospective analysis using ridge and linear multivariate regression analysis. Patient asthma management data were extracted from the hospital and general prac...

journal_title：Respiratory medicine

authors： Salamzadeh J,Wong IC,Hosker HS,Patel MG,Chrystyn H

更新日期：2005-06-01 00:00:00

abstract：INTRODUCTION:The duration of bronchodilator action of the long-acting beta agonist salmeterol when administered in the evening has not been investigated. In this study we have investigated whether a single evening dose of salmeterol, administered from the combination salmeterol/fluticasone (SFC) Accuhaler significantly...

journal_title：Respiratory medicine

authors： Masoli M,Weatherall M,Ayling J,Williams M,Beasley R

更新日期：2005-05-01 00:00:00

abstract：:Rounded atelectasis of the lung (RA) is a lesion well described in the medical literature, yet often very difficult to diagnose. In recent years, the widespread use of high-resolution imaging modalities employed in the struggle against cancer, coinciding with the peak of the asbestos epidemic, have boosted the detecti...

journal_title：Respiratory medicine

authors： Stathopoulos GT,Karamessini MT,Sotiriadi AE,Pastromas VG

更新日期：2005-05-01 00:00:00

abstract：:This study aims to investigate the possibility of additional value of leukotriene receptor antagonist (LTA) on dyspnea score, arterial blood gases (ABG), pulmonary function tests (PFTs), and quality of life (St. George QoL) in chronic obstructive pulmonary disease (COPD) patients. In this randomized, prospective, sing...

journal_title：Respiratory medicine

authors： Celik P,Sakar A,Havlucu Y,Yuksel H,Turkdogan P,Yorgancioglu A

更新日期：2005-04-01 00:00:00

abstract：:Rheumatoid arthritis (RA)-associated constrictive bronchiolitis is a severe condition with no established efficient treatment. A 55-year-old woman with seropositive RA developed rapidly progressive constrictive bronchiolitis confirmed by lung biopsy. Her clinical condition worsened despite steroids and azathioprine. T...

journal_title：Respiratory medicine

authors： Cortot AB,Cottin V,Miossec P,Fauchon E,Thivolet-Béjui F,Cordier JF

更新日期：2005-04-01 00:00:00